Spatial Memory Study

Nature Neuroscience 17: 1798–1803 (2014)

Spatial Memory Study

Study Details

• A study by Columbia University was done to see if taking cocoa flavanols once a day could improve performance in the area of the brain impacted by aging

• Healthy people between the ages of 50 and 69 took either a high level of cocoa flavanols (750mg) every day for 3 months or a low level (30mg), which acted as the control group

• Each person in the study was given a memory test and a brain scan to detect changes to areas of the brain affected by aging

The Results

Taking the same level of cocoa flavanols found in CocoaVia Memory+ every day was shown to boost brain performance and spatial memory

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24% Faster at Completing a Memory Test

Were able to complete memory tasks 24% faster than those in the control group.*

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62% More Blood Flow

Had 62% more blood flowing to the parts of the brain associated with age-related memory loss than they did before the study began†

*1997 ms vs 2627 ms reaction time, a difference of 630 ms.

†CBV of 2.9 at baseline vs 4.7 at follow-up in the high CF group

What did we learn?

Taking 750 mg of cocoa flavanols every day, the same amount in a serving of CocoaVia™ Memory+, improved brain function in areas of the brain responsible for memory loss as we age in just 12 weeks.

CocoaVia™ Memory+

  • Each serving delivers 750 mg of cocoa flavanols, the plant-based nutrient proven to boost memory when consumed daily at high levels
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Spatial Memory Study

Study Abstract

The dentate gyrus (DG) is a region in the hippocampal formation whose function declines in association with human aging and is therefore considered to be a possible source of age-related memory decline. Causal evidence is needed, however, to show that DG-associated memory decline in otherwise healthy elders can be improved by interventions that enhance DG function. We addressed this issue by first using a high-resolution variant of functional magnetic resonance imaging (fMRI) to map the precise site of age-related DG dysfunction and to develop a cognitive task whose function localized to this anatomical site. Then, in a controlled randomized trial, we applied these tools to study healthy 50–69-year-old subjects who consumed either a high or low cocoa flavanol–containing diet for 3 months. A high-flavanol intervention was found to enhance DG function, as measured by fMRI and by cognitive testing. Our findings establish that DG dysfunction is a driver of age-related cognitive decline and suggest non-pharmacological means for its amelioration.