The largest clinical study investigating the long-term impact of cocoa extract supplementation and multivitamins on health
The COSMOS Trial
What is the COSMOS Study?
The Cocoa Supplement and Multivitamin Outcomes Study (COSMOS):
- Largest study on a bioactive
- COSMOS Investigates whether cocoa extract supplementation or multivitamins can have a long-term benefit on health as we age
- Initiated and led by Brigham and Women's Hospital, an affiliate of Harvard Medical School
- Randomized, doubled-blinded, placebo controlled – the gold standard in research
STUDY PARTICIPANTS comprised of Healthy Women and Men from across the U.S.
60+ Years Old
AGE OF PARTICIPANTS
DURATION OF STUDY
OF COCOA FLAVANOLS were evaluated in the study, using a cocoa extract supplement.
This first publication from COSMOS has recently been released in The American Journal of Nutrition (AJCN), the premier clinical nutrition journal in the U.S.
In this 5-year study, participants who took the cocoa extract containing 500mg of cocoa flavanols experienced 27% improvement relative to important heart health outcomes relative to those in the placebo group
improvement on important heart health outcomes.
Including All Participants in the analysis.
improvement on important heart health outcomes
Including only those who said they took the supplement in the analysis
Cocoa Extract Supplement Materials
The cocoa extract supplement used in the study was specifically designed to meet the rigorous requirements of human clinical research.
500mg of cocoa flavanols were evaluated in the study using cocoa extract supplementation.
Leadership & Partners
COSMOS is a trial that was initiated and led by scientists from Brigham and Women’s Hospital, an affiliate of Harvard Medical School, and conducted in conjunction with the Fred Hutchinson Cancer Research Center.
It was co-founded by the NIH, Mars Edge and Pfizer, whose consumer healthcare business is now part of GSK Consumer Health Care.
Mars Edge, a segment of Mars, Incorporated to supporting human health through nutrition, contributed to the study in the form of investigator-initiated grants and in-kind funding, including the provision of test materials.
COSMOS Results Are Expected Soon!
Some of the inactive supplement ingredients might differ, e.g., clinical trials have specific requirements for capsule materials.